Edit |   |
Antigenic Specificity | MAD2 |
Clone | 17D10 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 50 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): Assay Dependent, Immunoprecipitation: 5 µg/mL, Western Blot: 2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MAD2 Monoclonal Antibody (17D10). mad2 is required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete. It inhibits the activity of the anaphase promoting complex by sequestering cdc20 until all chromosomes are aligned at the metaphase plate. |
Immunogen | n/a |
Other Names | MadL1 |
Gene, Accession # | Entrez: 4085; Uniprot: Q13257 |
Catalog # | MA1-5833 |
Price | |
Order / More Info | MAD2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |