| 产品详情 |
| Edit |   |
|---|
| Product Name | Naloxegol (oxalate) |
|---|
| Description | A peripherally acting antagonist of the μ-opioid receptor (Ki = 7.42 nM; pA2 = 7.95); selective for the μ-opioid receptor over the δ-opioid receptor (Ki = 866 nM); acts as a partial agonist of κ-opioid receptors in vitro (EC50 = 47 nM for [35S]GTPγS binding); reverses morphine-induced decreases in gastrointestinal motility and analgesia in a hot-plate assay in rats (ED50s = 23.1 and 55.4 mg/kg, respectively); exhibits minimal brain uptake in a rat brain perfusion model |
|---|
| Size | 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | AZ 13337019|NKTR-118 |
|---|
| Gene, Accession, CAS # | CAS: 1354744-91-4 |
|---|
| Catalog # | 23731-25 |
|---|
| Price | |
|---|
| Order / More Info | Naloxegol (oxalate) from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|