| 产品详情 |
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| Antigenic Specificity | FAS |
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| Clone | DX2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | Pacific Blue conjugate |
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| Size | 25 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FAS Monoclonal Antibody (DX2), Pacific Blue. Fas ligand (FasL, CD 95L) is a type-II-membrane protein, whose N-terminus is in the cytoplasm and its C-terminal region extends into the extracellular space. Its receptor Fas (CD 95, Apo-1) is a cell-surface-type-I-membrane protein and a member of the tumor necrosis factor (TNF) and nerve growth factor (NGF) receptor family. As a member of the TNF-cytokine family FasL induces apoptosis when interacting with its receptor Fas. FasL may exist as either membrane bound (45 kD) or soluble forms (26 kD). The soluble protein can be released from cells upon cleavage by metalloproteinases. Binding of FasL to Fas leads to oligomerization of the receptor and triggers apoptotic cell death through the interact |
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| Immunogen | n/a |
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| Other Names | ALPS1A, APO-1, APT1, Apo-1 Fas, CD95, FAS1, FASTM, TNFRSF6 |
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| Gene, Accession # | Entrez: 355; Uniprot: P25445 |
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| Catalog # | MHCD9528TR |
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| Price | |
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| Order / More Info | FAS Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18641321, 19949078, 25044944, 25488972 |
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| 产品资料 |
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