| 产品详情 |
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| Antigenic Specificity | FAS |
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| Clone | DX2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 10 µL for 10^6 cells or 1 µg/100 µL blood, Western Blot: Assay dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FAS Monoclonal Antibody (DX2). Many cells can be activated to undergo apoptosis following the interaction of selected ligands with cell surface receptors. One of the most studied receptors include the Fas receptor. Apoptosis mediated by both signaling cascades results in activation of a family of cystein proteases known as caspases. Engagement of Fas by its ligand, or by an appropriate antibody, results in the rapid induction of programmed cell death in susceptible cell lines. This process bypasses the usual long sequence of signaling enzymes and immediately activates preexisting caspases. |
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| Immunogen | n/a |
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| Other Names | ALPS1A, APO-1, APT1, Apo-1 Fas, CD95, FAS1, FASTM, TNFRSF6 |
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| Gene, Accession # | Entrez: 355; Uniprot: P25445 |
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| Catalog # | MA1-20163 |
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| Price | |
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| Order / More Info | FAS Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12239170, 16836648, 19187432, 19949078, 21441446, 21983117, 25488972, 27998726, 7523573 |
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