| 产品详情 |
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| Antigenic Specificity | CD152 (CTLA-4) |
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| Clone | 14D3 |
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| Host Species | Mouse |
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| Reactive Species | human, rhesus monkey |
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| Isotype | IgG2a, kappa |
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| Format | unconjugated, functional grade |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD152 (CTLA-4) Monoclonal Antibody (14D3), Functional Grade, eBioscience™. CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. |
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| Immunogen | n/a |
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| Other Names | CELIAC3, CTLA-4, GRD4, GSE, ICOS, IDDM12, CD152 isoform, celiac disease 3, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte antigen 4 |
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| Gene, Accession # | Entrez: 1493, 705673; Uniprot: P16410 |
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| Catalog # | 16-1529-82 |
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| Price | |
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| Order / More Info | CD152 (CTLA-4) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 22345473, 23152566, 26358640, 26482032, 28099147, 29371976 |
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