产品名称 PD-1 Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-35010
产品价格 现货询价,电话:010-67529703
产品规格 100 ug
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
Edit&nbsp
Antigenic SpecificityPD-1
CloneJ43
Host SpeciesArmenian Hamster
Reactive Speciesmouse
IsotypeIgG
Formatfluorescein (FITC) conjugate
Size100 ug
Concentrationn/a
ApplicationsFlow Cytometry: 2.0 µg/1x10^6 cells
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPD-1 Monoclonal Antibody (J43), FITC. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of ``danger signals'' such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems
Immunogenn/a
Other NamesCD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, programmed cell death protein 1, protein PD-1
Gene, Accession #Entrez: 18566; Uniprot: Q02242
Catalog #PA5-35010
Price
Order / More InfoPD-1 Antibody from INVITROGEN ANTIBODIES
Product Specific ReferencesPubMed: 26378075, 26466956
产品资料