| 产品详情 |
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| Antigenic Specificity | ACVR1C |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ACVR1C Antibody is a Rabbit Polyclonal antibody against ACVR1C. ACTR-IC (Activin receptor type 1C), also referred to as Activin receptor-like kinase 7 (ALK-7), is a type I serine/threonine kinase receptor. ACTA-IC contains an extracellular binding domain, an intracellular serine/threonine kinase domain preceded by a GS box and a transmembrane domain. It is expressed throughout the digestive and central nervous system and localizes to the cell surface. Four ACTR-IC transcripts are generated by alternative splicing. Transcript 1 is the functional full length receptor, transcript 2 lacks a complete receptor binding domain and transcripts 3 and 4 are soluble proteins that lack a transmembrane domain. ACTR-IC is a receptor for Activin AB, Activin B and Nodal. In pancreatic cells, ACTR-IC forms a complex with Activin receptor type IIB (ACTR-IIB). The kinase domain of ACTR-IC can induce Smad2 and Smad3 signalling pathways. In some cell lines, ACTR-IC overexpression induces apoptosis and inhibits proliferation. |
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| Immunogen | Recombinant protein of human ACVR1C. |
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| Other Names | Activin receptor type IC; ACTR-IC; Activin receptor-like kinase 7; ALK-7; ACVR1C; ALK7; ACVRLK7; Activin receptor type-1C |
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| Gene, Accession # | ACVR1C, Gene ID: 130399, SwissProt: Q8NER5 |
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| Catalog # | abx000813 |
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| Price | |
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| Order / More Info | ACVR1C Antibody from ABBEXA |
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| Product Specific References | n/a |
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