产品名称 A-971432 from CAYMAN CHEMICAL COMPANY
产品货号 25326-5
产品价格 现货询价,电话:010-67529703
产品规格 5 mg
产品品牌 CAYMAN CHEMICAL COMPANY
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Product NameA-971432
DescriptionAn S1P5 agonist that is selective for S1P5 over S1P1 and S1P3 (IC50s = 0.006, 0.362, and >10 µM, respectively); inhibits forskolin-induced cAMP production in CHO cells expressing S1P5 (EC50 = 4.1 nM); increases electrical resistance of hCMEC/D3 cells in an in vitro blood-brain barrier model at 1 µM; attenuates blood-brain barrier leakage in an R6/2 transgenic mouse model of Huntington's disease at 0.1 mg/kg; decreases the number of errors made in a horizontal ladder task and increases latency to fall in the rotarod test in R6/2 mice at 0.1 mg/kg; increases spontaneous alternation in the t-maze in aged mice at 0.1 mg/kg,
Size5 mg
Concentrationn/a
Applicationsn/a
Other NamesA971432 S1P-1 3 5 R2 BBB cyclic adenosine monophosphate Chinese hamster ovary R-6
Gene, Accession, CAS #CAS: 1240308-45-5
Catalog #25326-5
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Order / More InfoA-971432 from CAYMAN CHEMICAL COMPANY
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