产品详情 |
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Antigenic Specificity | Myeloperoxidase |
Clone | 2C7 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 40 µg |
Concentration | n/a |
Applications | Flow Cytometry: 1:50-1:100, Immunohistochemistry (Frozen): 1:500-1:5000, Immunohistochemistry (Paraffin): 1:500-1:5000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Myeloperoxidase Monoclonal Antibody (2C7). Myeloperoxidase (MPO) is a hemoprotein that is abundantly expressed in neutrophils and secreted during their activation. Native Myeloperoxidase is represented as a covalently bound tetrameric complex of two glycosylated alpha chains with a molecular weight range of 59 - 64 kDa, and two unglycosylated beta chains (MW ~14 kDa) with total MW ~150 kDa and a theoretical pI of 9.2. Traditionally, myeloperoxidase was considered as a main target of anti-neutrophil cytoplasm antibodies (ANCA), the serological markers for certain systemic vasculities such as periarteriitis nodosa, microscopic polyarteriitis and pulmonary eosinophilic granulomatosis (Churg-Strauss syndrome). Low to moderate anti-myeloperoxida |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 4353; Uniprot: P05164 |
Catalog # | MA1-34067 |
Price | |
Order / More Info | Myeloperoxidase Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 25548252 |
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