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| Antigenic Specificity | CD195 (CCR5) |
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| Clone | NP-6G4 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 100 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.125 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD195 (CCR5) Monoclonal Antibody (NP-6G4), PE, eBioscience™. Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. Among them, CCR5 (CC-CKR-5) is a principal coreceptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells. CCR5 is required for the infection by HIV-1, HIV-2, and SIV. The beta-chemokines RANTES, MIP-alpha and MIP-beta are the ligands for CCR5 and prevent infection by M-tropic HIV-1. CXC5 associates with the surf |
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| Immunogen | n/a |
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| Other Names | C-C CKR-5, CC-CKR-5, HIV-1 fusion coreceptor, CHEMR13, CD195 antigen, CMKBR5 |
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| Gene, Accession # | Entrez: 1234; Uniprot: P51681 |
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| Catalog # | 12-1956-42 |
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| Order / More Info | CD195 (CCR5) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25517314, 26107738 |
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