产品名称 CD195 (CCR5) Antibody from BIOLEGEND
产品货号 313711
产品价格 现货询价,电话:010-67529703
产品规格 25 tests
产品品牌 BIOLEGEND
产品概述
产品详情
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Antigenic SpecificityCD195 (CCR5)
CloneHEK/1/85a
Host SpeciesRat
Reactive Specieshuman
IsotypeIgG2a, κ
FormatAlexa Fluor® 647 conjugate
Size25 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionAlexa Fluor® 647 anti-human CD195 (CCR5). CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
ImmunogenCHO cells transfected with human CCR5
Other NamesCCR5, C-C chemokine receptor type 5, HIV-1 fusion co-receptor
Gene, Accession #Gene ID: 1234
Catalog #313711
Price
Order / More InfoCD195 (CCR5) Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 22848746,24748497,25179963
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