产品详情 |
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Antigenic Specificity | DKK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Western Blot: 0.5-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DKK1 Polyclonal Antibody. DKK1 is a 266 amino acid secreted protein with two cysteine rich regions and belonging to the dickkopf family. It is involved in embryonic development through its inhibition of the WNT signaling pathway and in the reentry into the cell cycle of human adult stem cells from bone marrow. Its loss of expression plays a role in development or progression of malignant melanoma. It decreases melanocyte function and is a key player in multiple myeloma bone disease. It is a potential prognostic and diagnostic marker for breast cancer patients with poor prognosis. |
Immunogen | n/a |
Other Names | UNQ492/PRO1008, DKK-1, SK, dickkopf related protein-1, dickkopf-1 like, dickkopf-related protein 1, hDkk-1 |
Gene, Accession # | Entrez: 13380, 22943; Uniprot: O54908, O94907 |
Catalog # | PA5-23187 |
Price | |
Order / More Info | DKK1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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