| 产品详情 |
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| Antigenic Specificity | TRAF6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 10 µg/mL, Immunofluorescence: 20 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRAF6 Polyclonal Antibody. Signals from the IL-1 receptor (IL-1R)/Toll-like receptor (TLR) and TNF receptor (TNFR) superfamilies are critical for regulating the function of antigen-presenting cells. Signals transduced by these molecules lead to increased expression and activation of transcription factors such as NF-kappa-B. TNF receptor-associated factor 6 (TRAF6) is unique in that it is a signaling adapter molecule common to both families. TRAF6 is important in cytokine production, dendritic cell (DC) maturation, and the T cell stimulatory capacity of DCs in response to TLR and CD40 ligands. It can be activated in the IL-1R/TLR signaling pathway by IL-1 receptor-associated kinase 1 (IRAK-1) or by other TLR adaptor molecules such as TRIF. A |
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| Immunogen | n/a |
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| Other Names | MGC:3310, RNF85; E3 ubiquitin-protein ligase TRAF6; RING finger protein 85; interleukin-1 signal transducer |
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| Gene, Accession # | Entrez: 22034, 311245, 7189; Uniprot: B5DF45, P70196, Q9Y4K3 |
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| Catalog # | PA5-20019 |
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| Price | |
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| Order / More Info | TRAF6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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