| 产品详情 |
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| Antigenic Specificity | SQSTM1/p62 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, monkey, mouse, rat (predicted: hamster) |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | IF, IHC, ICC, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal Picoband™ antibody for Sequestosome-1(SQSTM1) detection. Tested with WB, IHC-P, IHC-F, ICC, IF in Human;Mouse;Monkey;Rat. No cross reactivity with other proteins. SQSTM1(Sequestosome-1), also known as Ubiquitin-Binding Protein P62 or P62, is a protein that in humans is encoded by the SQSTM1 gene. The Src homology type 2 (SH2) domain is a highly conserved motif of about 100 amino acids which mediates protein-protein interactions by binding to phosphotyrosine.p56-lck, a T-cell-specific src family tyrosine kinase with an SH2 domain, is involved in T-cell signal transduction. The International Radiation Hybrid Mapping Consortium mapped the p62 gene to chromosome 5q35. Park et al. (1995) found that the p56-lck SH2 domain binds to p62 at the ser59 of p62 only when that serine is phosphorylated. Joung et al. (1996) expressed epitope-tagged p62 in Hela cells and showed that the expressed protein bound to the lck SH2 domain and that this binding was dependent on the N-terminal 50 amino acids of p62 but not on the tyrosine residue in this region. |
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| Immunogen | n/a |
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| Other Names | Sequestosome-1;EBI3-associated protein of 60 kDa;EBIAP;p60;Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa;Ubiquitin-binding protein p62;SQSTM1;ORCA, OSIL; |
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| Gene, Accession # | SQSTM1, UniProt: Q13501 |
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| Catalog # | PB9444 |
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| Price | |
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| Order / More Info | SQSTM1/p62 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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