产品名称 TIM3 Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-18470
产品价格 现货询价,电话:010-67529703
产品规格 100 ug
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityTIM3
Clonepolyclonal
Host SpeciesGoat
Reactive Specieshuman
Isotypen/a
Formatpurified
Size100 ug
Concentrationn/a
Applicationspeptide-ELISA: 1:32000, Western Blot: 0.3-1.0 µg/mL
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DescriptionTIM3 Polyclonal Antibody. TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells. TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region. TIM3 is involved in macrophage activation and induction of autoimmune diseases. Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance. Pathological significance of TIM3 has been attributed to Experimental autoimmune encephalomyelitis (EAE), a Th-1 depe
Immunogenn/a
Other NamesHAVCR2; TIM3; hepatitis A virus cellular receptor 2; FLJ14428; KIM-3; TIMD3; Tim-3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; kidney injury molecule-3
Gene, Accession #Entrez: 84868; Uniprot: Q8TDQ0
Catalog #PA5-18470
Price
Order / More InfoTIM3 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料