产品名称 TIM3 Antibody from INVITROGEN ANTIBODIES
产品货号 MA5-17955
产品价格 现货询价,电话:010-67529703
产品规格 250 ug
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityTIM3
Clone25F.1D6
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a, kappa
Formatpurified
Size250 ug
Concentrationn/a
ApplicationsFlow Cytometry: 1 µg /1x10^6 cells, Immunohistochemistry: Assay Dependent
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DescriptionTIM3 Monoclonal Antibody (25F.1D6). TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells. TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region. TIM3 is involved in macrophage activation and induction of autoimmune diseases. Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance. Pathological significance of TIM3 has been attributed to Experimental autoimmune encephalomyelitis (EAE), a
Immunogenn/a
Other NamesHAVCR2, hepatitis A virus cellular receptor 2, FLJ14428, KIM-3, TIMD3, T cell immunoglobulin mucin 3, kidney injury molecule 3
Gene, Accession #Entrez: 171285; Uniprot: Q8VIM0
Catalog #MA5-17955
Price
Order / More InfoTIM3 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料