| 产品详情 |
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| Antigenic Specificity | TIM3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human and mouse |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western blot, IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Polyclonal Antibody to detect TIM3 in human and mouse samples. As a member of the T cell immunoglobulin and mucin domain (TIM) family, Tim-3 is reported to promote or terminate Th1 immunity and is thought to influence a range of inflammatory conditions. It is constitutively expressed in a subset of murine IFNgamma-secreting Th1 cells, but not Th2 cells, in both human and mice. Additionally, Tim-3 is expressed dendritic cells, and by a subset of CD4+ cells where its levels of expression increase upon anti-CD3/28 stimulation. This molecule is also highly expressed in in vitro polarized Th1 cells, and at lower levels in Th17 cells. It is known to synergize with Toll-like receptors and is thought to regulate Th1 and Th17 cytokine secretion. |
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| Immunogen | KLH-conjugated synthetic peptide of human TIM3 |
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| Other Names | TIM3, TIMD3, Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3 |
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| Gene, Accession # | Gene ID: 84868, Accession: Q8TDQ0 |
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| Catalog # | A1390-100 |
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| Price | |
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| Order / More Info | TIM3 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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