| 产品详情 |
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| Antigenic Specificity | CTLA4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | WB, IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal unconjugated antibody to detect CTLA4 in human samples. CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
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| Immunogen | KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human IDDM12. |
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| Other Names | Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4, CD152 |
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| Gene, Accession # | Gene ID: 1493, Accession: P16410 |
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| Catalog # | A1083-100 |
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| Price | |
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| Order / More Info | CTLA4 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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