| 产品详情 |
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| Antigenic Specificity | K-Ras |
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| Clone | F132-62 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: Assay-dependent, Immunofluorescence: 1.5-2.5 µg/mL, Immunohistochemistry (Frozen): 4-6 µg/mL, Immunohistochemistry (Paraffin): 4-6 µg/mL, Immunoprecipitation: 3-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | K-Ras Monoclonal Antibody (F132-62). This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive |
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| Immunogen | n/a |
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| Other Names | C-K-RAS, RASK, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, RASK2, GTPase KRas, K-Ras 2, K-ras p21 protein, Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog, PR310 c-K-ras oncogene, c-Ki-ras, c-Kirsten-ras protein, cellular c-Ki-ras2 |
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| Gene, Accession # | Entrez: 16653, 24525, 3845; Uniprot: P01116, P08644, P32883 |
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| Catalog # | MA1-91046 |
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| Price | |
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| Order / More Info | K-Ras Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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