产品详情 |
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Product Name | Pralidoxime (chloride) |
Description | Reactivates AChE that has been deactivated by binding of organophosphates to its esteratic site; binds to the anionic site of AChE and displaces the phosphate from the esteratic site through formation of phosphate-pralidoxime conjugates; reactivates paraoxon- and diisopropyl fluorophosphate-inactivated human RBC AChE with IC50 shifts of 0.3 and 0.8 nM per µM of pralidoxime, respectively; at a concentration of 10 µM, reactivates human RBC AChE that has been inactivated by chlorpyrifos, diazinon, and malathion by 17, 61, and 36%, respectively; binds to sarin-bound hAChE (Kd = 25.72 µM) and inhibits sarin-induced AChE deactivation (IC50 = 1.21 mM) in hemoglobin-free erythrocyte ghosts |
Size | 1 g |
Concentration | n/a |
Applications | n/a |
Other Names | 2-PAM |
Gene, Accession, CAS # | CAS: 51-15-0 |
Catalog # | 23666-1 |
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Order / More Info | Pralidoxime (chloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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