| 产品详情 |
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| Product Name | Pralatrexate |
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| Description | A DHFR inhibitor (Ki = 13.4 pM) and antifolate; inhibits growth of acute lymphocytic leukemia cells (IC50 = 0.04 µM), MDA-468, SK-BR-3, and ZR-75-1 breast cancer cells (IC50s = 0.11, 0.28, and 0.26 µM, respectively), and SK-LC8 and SK-LC16 NSCLC cells (IC50s = 0.42 and 0.11 µM, respectively); increases median survival in vivo in an H9 T cell lymphoma mouse xenograft model |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 10-Propargyl-10-deazaaminopterin|NSC 754230|PDX |
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| Gene, Accession, CAS # | CAS: 146464-95-1 |
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| Catalog # | 23689-50 |
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| Order / More Info | Pralatrexate from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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