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| Product Name | p38 MAPK Inhibitor VIII |
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| Description | An inhibitor of p38α (IC50 = 39 nM) and p38β MAP kinases with 82 and 93% inhibition, respectively, in a kinase assay (1 µM); selective for p38α and 38β, lacking activity at p38γ, p38δ, ERK1/2, and JNK1 at 1 µM; inhibits IL-1β, TNF-α, IL-6, IL-8, and IL-10, but not IFN-γ release from human peripheral blood mononuclear cells (IC50s = 30, 5, 17, 4, 10, and >1,000 nM, respectively); decreases ear swelling in mouse models of allergic and chronic irritative contact dermatitis (0.5 mg/ear, topical) |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ?p38 MAP Kinase Inhibitor VIII|EO 1428|p38 Mitogen-activated Protein Kinase Inhibitor VIII |
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| Gene, Accession, CAS # | CAS: 321351-00-2 |
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| Catalog # | 21229-5 |
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| Order / More Info | p38 MAPK Inhibitor VIII from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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