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| Product Name | Diethylstilbestrol |
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| Description | Diethylstilbestrol (DES) is a synthetic estrogen receptor agonist that was prescribed to pregnant women in the late 1930s. It was banned in 1971 because of possible links to increased risk of breast cancer in mothers along with congenital abnormalities and increased risk of cancer in offspring.{12906} DES is structurally related to, and is as potent as, estradiol in most assays, with a longer half-life. It has a relative binding affinity to sex hormone binding globulin (SHBG) of 0.2 compared to estradiol which has a relative binding affinity of 100. A concentration of 20 µM DES, displaces 30 ± 13% of 3H-estradiol from SHBG in serum.{12906,12990} |
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| Size | 5000 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | synthetics receptors agonists pregnant pregnancies linked breasts cancers congenital abnormalities abnormality offspring 3H-estradiols binding affinities affinity sexes hormones globulins SHBG estrogens |
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| Gene, Accession, CAS # | CAS: 56-53-1 |
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| Catalog # | 10006876-5 |
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| Order / More Info | Diethylstilbestrol from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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