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| Product Name | AZD 3463 |
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| Description | An ALK and IGF-1R inhibitor; inhibits ALK (IC50 = 15 nM); inhibits the proliferation of neuroblastoma cells with WT ALK (IC50s = 2.8-21.3 µM) or ALK containing activating mutations (IC50s = 1.7 and 16.49 µM for ALKF1174L and ALKD1091N, respectively); reduces tumor growth in neuroblastoma mouse xenograft models expressing WT ALK or the ALKF1174L mutation at 15 mg/kg per day for 21 days |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 1356962-20-3 |
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| Catalog # | 26172-10 |
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| Price | |
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| Order / More Info | AZD 3463 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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