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| Antigenic Specificity | ABL1 (pY245) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC, IF/ICC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ABL1 is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t (9;22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. This ABL1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y245 of human ABL1. |
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| Immunogen | Human ABL1 (phospho-Tyr245). |
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| Other Names | ABL1; ABL; JTK7; bcr/abl; c-ABL; p150; v-abl; ABL proto-oncogene 1 non-receptor tyrosine kinase; v-abl Abelson murine leukemia viral oncogene homolog 1; c-abl oncogene 1 receptor tyrosine kinase; c-abl oncogene 1 non-receptor tyrosine kinase; bcr/c-abl oncogene protein; proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; tyrosine-protein kinase ABL1; Abelson tyrosine-protein kinase 1; c-ABL1; Abelson murine leukemia viral oncogene homolog 1; Anti-ABL1; Anti-ABL; Anti-JTK7; Anti-bcr/abl; Anti-c-ABL; Anti-p150; Anti-v-abl; Anti-ABL proto-oncogene 1 non-receptor tyrosine kinase; Anti-v-abl Abelson murine leukemia viral oncogene homolog 1; Anti-c-abl oncogene 1 receptor tyrosine kinase; Anti-c-abl oncogene 1 non-receptor tyrosine kinase; Anti-bcr/c-abl oncogene protein; Anti-proto-oncogene c-Abl; Anti-proto-oncogene tyrosine-protein kinase ABL1; Anti-tyrosine-protein kinase ABL1; Anti-Abelson tyrosine-protein kinase 1; Anti-c-ABL1; Anti-Abelson murine leukemia viral oncogene homolog 1; ABL proto-oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-abl oncogene 1, non-receptor tyrosine kinase; Anti-ABL proto-oncogene 1, non-receptor tyrosine kinase; Anti-c-abl oncogene 1, receptor tyrosine kinase; Anti-c-abl oncogene 1, non-receptor tyrosine kinase; ABL1 Pair; ABL Pair; JTK7 Pair; bcr/abl Pair; c-ABL Pair; p150 Pair; v-abl Pair; ABL proto-oncogene 1, non-receptor tyrosine kinase Pair; v-abl Abelson murine leukemia viral oncogene homolog 1 Pair; c-abl oncogene 1, receptor tyrosine kinase Pair; c-abl oncogene 1, non-receptor tyrosine kinase Pair; bcr/c-abl oncogene protein Pair; proto-oncogene c-Abl Pair; proto-oncogene tyrosine-protein kinase ABL1 Pair; tyrosine-protein kinase ABL1 Pair; Abelson tyrosine-protein kinase 1 Pair; c-ABL1 Pair; Abelson murine leukemia viral oncogene homolog 1 Pair; Anti-ABL1 Pair; Anti-ABL Pair; Anti-JTK7 Pair; Anti-bcr/abl Pair; Anti-c-ABL Pair; Anti-p150 Pair; Anti-v-abl Pair; Anti-ABL proto-oncogene 1, non-receptor tyrosine kinase Pair; Anti-v-abl Abelson murine leukemia viral oncogene homolog 1 Pair; Anti-c-abl oncogene 1, receptor tyrosine kinase Pair; Anti-c-abl oncogene 1, non-receptor tyrosine kinase Pair; Anti-bcr/c-abl oncogene protein Pair; Anti-proto-oncogene c-Abl Pair; Anti-proto-oncogene tyrosine-protein kinase ABL1 Pair; Anti-tyrosine-protein kinase ABL1 Pair; Anti-Abelson tyrosine-protein kinase 1 Pair; Anti-c-ABL1 Pair; Anti-Abelson murine leukemia viral oncogene homolog 1 Pair |
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| Gene, Accession # | ABL1, Gene ID: 25, SwissProt: P00519 |
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| Catalog # | abx031821 |
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| Price | |
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| Order / More Info | ABL1 (pY245) Antibody from ABBEXA |
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| Product Specific References | n/a |
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