| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | ABL1 (pY204) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 50 µl, 100 µl, 200 µl |
|---|
| Concentration | > 1 mg/ml |
|---|
| Applications | WB, IF/ICC. RUO |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | ABL1 (pY204) Antibody is a Rabbit Polyclonal antibody against ABL1 (pY204). The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. |
|---|
| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y204 of human ABL1. |
|---|
| Other Names | ABL1; ABL; JTK7; bcr/abl; c-ABL; p150; v-abl; ABL proto-oncogene 1 non-receptor tyrosine kinase; v-abl Abelson murine leukemia viral oncogene homolog 1; c-abl oncogene 1 receptor tyrosine kinase; c-abl oncogene 1 non-receptor tyrosine kinase; bcr/c-abl oncogene protein; proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; tyrosine-protein kinase ABL1; Abelson tyrosine-protein kinase 1; c-ABL1; Abelson murine leukemia viral oncogene homolog 1; Anti-ABL1; Anti-ABL; Anti-JTK7; Anti-bcr/abl; Anti-c-ABL; Anti-p150; Anti-v-abl; Anti-ABL proto-oncogene 1 non-receptor tyrosine kinase; Anti-v-abl Abelson murine leukemia viral oncogene homolog 1; Anti-c-abl oncogene 1 receptor tyrosine kinase; Anti-c-abl oncogene 1 non-receptor tyrosine kinase; Anti-bcr/c-abl oncogene protein; Anti-proto-oncogene c-Abl; Anti-proto-oncogene tyrosine-protein kinase ABL1; Anti-tyrosine-protein kinase ABL1; Anti-Abelson tyrosine-protein kinase 1; Anti-c-ABL1; Anti-Abelson murine leukemia viral oncogene homolog 1; ABL proto-oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-abl oncogene 1, non-receptor tyrosine kinase; Anti-ABL proto-oncogene 1, non-receptor tyrosine kinase; Anti-c-abl oncogene 1, receptor tyrosine kinase; Anti-c-abl oncogene 1, non-receptor tyrosine kinase; ABL1 Pair; ABL Pair; JTK7 Pair; bcr/abl Pair; c-ABL Pair; p150 Pair; v-abl Pair; ABL proto-oncogene 1, non-receptor tyrosine kinase Pair; v-abl Abelson murine leukemia viral oncogene homolog 1 Pair; c-abl oncogene 1, receptor tyrosine kinase Pair; c-abl oncogene 1, non-receptor tyrosine kinase Pair; bcr/c-abl oncogene protein Pair; proto-oncogene c-Abl Pair; proto-oncogene tyrosine-protein kinase ABL1 Pair; tyrosine-protein kinase ABL1 Pair; Abelson tyrosine-protein kinase 1 Pair; c-ABL1 Pair; Abelson murine leukemia viral oncogene homolog 1 Pair; Anti-ABL1 Pair; Anti-ABL Pair; Anti-JTK7 Pair; Anti-bcr/abl Pair; Anti-c-ABL Pair; Anti-p150 Pair; Anti-v-abl Pair; Anti-ABL proto-oncogene 1, non-receptor tyrosine kinase Pair; Anti-v-abl Abelson murine leukemia viral oncogene homolog 1 Pair; Anti-c-abl oncogene 1, receptor tyrosine kinase Pair; Anti-c-abl oncogene 1, non-receptor tyrosine kinase Pair; Anti-bcr/c-abl oncogene protein Pair; Anti-proto-oncogene c-Abl Pair; Anti-proto-oncogene tyrosine-protein kinase ABL1 Pair; Anti-tyrosine-protein kinase ABL1 Pair; Anti-Abelson tyrosine-protein kinase 1 Pair; Anti-c-ABL1 Pair; Anti-Abelson murine leukemia viral oncogene homolog 1 Pair |
|---|
| Gene, Accession # | ABL1, Gene ID: 25, SwissProt: P00519 |
|---|
| Catalog # | abx000093 |
|---|
| Price | |
|---|
| Order / More Info | ABL1 (pY204) Antibody from ABBEXA |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|