产品详情 |
Edit |   |
Antigenic Specificity | TRPV5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | lyophilized |
Applications | Immunohistochemistry: 1:300-1:2000, Western Blot: 1:300-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRPV5 Polyclonal Antibody. Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating. Homotetramer and probably heterotetramer with TRPV6. Interacts with TRPV6. Interacts with S100A10 and probably with the ANAX2-S100A10 heterotetramer. The interaction with S100A10 is required for the trafficking to the plasma membrane. Interacts with c |
Immunogen | n/a |
Other Names | Transient receptor potential cation channel subfamily V member 5, TrpV5, osm-9-like TRP channel 3, OTRPC3, Epithelial calcium channel 1, ECaC1, Calciu |
Gene, Accession # | Entrez: 194352; Uniprot: P69744 |
Catalog # | OSR00059W |
Price | |
Order / More Info | TRPV5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|