| 产品详情 |
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| Antigenic Specificity | ITM2B |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. This ITM2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-247 amino acids from the C-terminal region of human ITM2B. |
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| Immunogen | Human ITM2B. |
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| Other Names | ITM2B; BRI; BRI2; Integral membrane protein 2B; Immature BRI2; Protein E25B; Transmembrane protein BRI; membrane form; Mature BRI2; BRI2 intracellular domain; BRI2C; soluble form; Bri23 peptide; ABri23; C-terminal peptide; P23 peptide; ABRI; BRICD2B; E25B; E3-16; FBD; BRICHOS domain containing 2B; OTTHUMP00000018394 |
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| Gene, Accession # | ITM2B, SwissProt: Q9Y287 |
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| Catalog # | abx027251 |
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| Price | |
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| Order / More Info | ITM2B Antibody from ABBEXA |
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| Product Specific References | n/a |
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