| 产品详情 |
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| Antigenic Specificity | CD3 |
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| Clone | OKT3 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1 µg/mL, Functional Assay: Assay Dependent, Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunohistochemistry (Frozen): Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD3 Monoclonal Antibody (OKT3). The CD3 subunit complex which is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules and this association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 |
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| Immunogen | n/a |
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| Other Names | FLJ18683, T3E, TCRE, CD3-epsilon, CD3e antigen, epsilon polypeptide TiT3 complex, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, CD3-DELTA, T3D, CD3 antigen, delta subunit, CD3 delta, CD3d antigen, delta polypeptide TiT3 complex, OKT3, delta chain, T-cell receptor T3 delta chain, T-cell surface glycoprotein CD3 delta chain |
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| Gene, Accession # | Entrez: 915, 916, 917, 919; Uniprot: P04234, P07766, P09693, P20963 |
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| Catalog # | MA1-10175 |
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| Price | |
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| Order / More Info | CD3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12218122, 27941243 |
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