| 产品详情 |
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| Antigenic Specificity | HSD11B2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HSD11B2 Polyclonal Antibody. There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects c |
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| Immunogen | n/a |
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| Other Names | AME, AME1, HSD2, HSD11K, SDR9C3 |
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| Gene, Accession # | Entrez: 3291; Uniprot: P80365 |
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| Catalog # | PA5-50682 |
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| Price | |
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| Order / More Info | HSD11B2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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