| 产品详情 |
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| Antigenic Specificity | Puma BH3 Domain |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC, IF/ICC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis. This Puma BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-154 amino acids from human Puma BH3 Domain. |
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| Immunogen | Human Puma BH3 Domain. |
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| Other Names | BBC3; PUMA; Bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis |
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| Gene, Accession # | Accession: NP_001120712.1, NP_001120713.1, NP_001120714.1, NP_055232.1, SwissProt: Q9BXH1 |
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| Catalog # | abx027261 |
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| Price | |
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| Order / More Info | Puma BH3 Domain Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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