产品详情 |
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Antigenic Specificity | Hsp90a |
Clone | K41007 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence Microscopy (IF), ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Hsp90α. Hsp90 is one of the most abundant molecular chaperones. It modulates the stability and transport of a diverse set of critical factors, including regulatory, metabolic, organizational, and signaling proteins. There are two major isoforms: α and β. In humans, the Hsp90β isoform is constitutively expressed, whereas the Hsp90α isoform is expressed under stress conditions. The Hsp90 dimer acts in concert with other chaperones and is regulated by a number of co-chaperones/accessory proteins. Upregulation of Hsp90 is associated with tumor progression, invasion and formation of metastases, and development of drug resistance. Therefore Hsp90 has emerged as an important target for cancer treatment. |
Immunogen | Amino acids 702-716 of human HSP90α |
Other Names | Heat Shock Protein 90kDa Alpha (Cytosolic), Class A Member 1, HSPC1, HSP86, HSP89A, HSPCAL4, LAP2, EL52 and HSP90N, HSP90a, HSP90 alpha |
Gene, Accession # | Gene ID: 3320 |
Catalog # | 661702 |
Price | |
Order / More Info | Hsp90a Antibody from BIOLEGEND |
Product Specific References | n/a |
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