产品详情 |
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Antigenic Specificity | GPX4 |
Clone | 1H11 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | ELISA: Assay dependent, Immunoprecipitation: 1-2 µL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GPX4 Monoclonal Antibody (1H11). Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduc |
Immunogen | n/a |
Other Names | GPX4, Phospholipid hydroperoxide glutathione peroxidase |
Gene, Accession # | Entrez: 2879, 29328, 625249; Uniprot: O70325, P36969, P36970 |
Catalog # | LF-MA0085 |
Price | |
Order / More Info | GPX4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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