产品详情 |
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Antigenic Specificity | GABBR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: Assay-Dependent, Western Blot: 0.6 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GABBR2 Polyclonal Antibody. GABA B receptor is a G-protein-coupled inhibitory receptor of gamma-aminobutyric acid (GABA), and has important functions in brain by inhibition of adenylyl cyclase and modulation of G-protein-gated Ca2+ and K+ channels. GABA B receptor is comprised of two subunits, GB1 and GB2 with N-terminal extracellular and C-terminal intracellular domains. The GB1 subunit plays a critical role in ligand binding, whereas the GB2 subunit contains the determinants required for G-protein signaling. Multiple allosteric interactions between the two subunits are required for correct functioning of the receptor. There are two N-terminal splice variants of GB1 subunit, termed GB1a and GB1b; their expression in the central nervous sys |
Immunogen | n/a |
Other Names | RP23-337N2.1, GABABR2, Gb2, Gm425, Gpr51, G protein-coupled receptor 51, G-protein coupled receptor 51, GABA-B receptor 2, GABA-B-R2, GABA-BR2, gamma-aminobutyric acid type B receptor subunit 2, gamma-aminobutyric acid type B receptor, subunit 2, ortholog of human G protein-coupled receptor 51 GPR51 |
Gene, Accession # | Entrez: 242425, 83633; Uniprot: O88871, Q80T41 |
Catalog # | PA1-10032 |
Price | |
Order / More Info | GABBR2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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