| 产品详情 |
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| Product Name | FX1 |
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| Description | A BCL6 inhibitor (IC50 = ~35 µM); selective for BCL6 over a panel of 50 kinases at 10 µM; reduces recruitment of the BCL6 corepressor proteins SMRT and BCOR to the BCL6 target loci CDKN1A, CD69, and CXCR4 in a ChIP assay at 50 µM; represses growth of Farage, SUDLH-6, DOHH-2, OCI-Ly7, RCK8, SUDHL-4, OCI-Ly1, and SC-1 BCL6-dependent cell lines (GI50s = 16-54 µM); reduces tumor volume in an HBL-1 large B cell lymphoma mouse xenograft model at 50 mg/kg |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FX-1 BCL-6 CDKN-1A CD-69 CXCR-4 SUDLH6 DOHH-2 OC-Ly7 OCly-7 RCK-8 SUDHL4 OCILy1 OC-ILY1 OCILY1B50 Karpas433 OCILy19 OCIly-19 HBL1 |
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| Gene, Accession, CAS # | CAS: 1426138-42-2 |
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| Catalog # | 23908-5 |
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| Price | |
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| Order / More Info | FX1 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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