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| Antigenic Specificity | p53AIP1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 10 µg/mL, Immunofluorescence: 20 µg/mL, Western Blot: 4-8 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p53AIP1 Polyclonal Antibody. The p53 tumor-suppressor protein can induce apoptosis through transcriptional activation of several genes. One such protein p53AIP was initially identified through direct cloning of p53 binding sequences from human genomic DNA. Its expression is inducible by p53 following p53 phosphorylation on Ser-46, and ectopic expression of p53AIP leads to apoptotic cell death. Both the phosphorylation of p53 and the induction of p53AIP were blocked by inhibiting the expression of p53DINP1 by the introduction of antisense oligonucleotides to p53DINP1, suggesting that the apoptosis associated with p53AIP expression is regulated by p53DINP1. Finally, as adenovirus-mediated introduction of p53AIP has been shown to suppress tumo |
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| Immunogen | n/a |
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| Other Names | P53AIP1; p53-regulated apoptosis-inducing protein 1 |
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| Gene, Accession # | Entrez: 63970; Uniprot: Q9HCN2 |
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| Catalog # | PA5-20355 |
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| Price | |
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| Order / More Info | p53AIP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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