产品详情 |
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Antigenic Specificity | BATF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, canine, equine, guinea pig, human, mouse, rabbit, rat, yeast, zebrafish |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 0.2-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BATF Polyclonal Antibody. BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination. |
Immunogen | n/a |
Other Names | Basic leucine zipper transcription factor, ATF-like, B-ATF, BATF1, SFA-2, SFA2 |
Gene, Accession # | Entrez: 100057690, 100338089, 100714129, 10538, 299206, 53314, 564589, 611951, 617628; Uniprot: D4A7E1, E1BD44, F1QW76, O35284, Q16520 |
Catalog # | PA5-40595 |
Price | |
Order / More Info | BATF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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