产品详情 |
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Antigenic Specificity | BATF |
Clone | MBM7C7 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | PerCP-eFluor 710 conjugate |
Size | 100 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.125 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BATF Monoclonal Antibody (MBM7C7), PerCP-eFluor 710, eBioscience™. BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination. |
Immunogen | n/a |
Other Names | BATF, B-cell activating transcription factor, BATF1, basic leucine zipper transcriptional factor ATF-like, SF-HT-activated gene 2 protein, SFA-2, SFA2 |
Gene, Accession # | Entrez: 10538; Uniprot: Q16520 |
Catalog # | 46-9860-42 |
Price | |
Order / More Info | BATF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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