产品详情 |
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Antigenic Specificity | CMPK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50-1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CMPK2 Polyclonal Antibody. UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response |
Immunogen | n/a |
Other Names | TMPK2, TYKi, UMP-CMPK2, UMP-CMP kinase 2, mitochondrial, cytidylate kinase 2, mitochondrial UMP-CMP kinase, thymidine monophosphate kinase 2, thymidylate kinase family LPS-inducible member |
Gene, Accession # | Entrez: 129607; Uniprot: Q5EBM0 |
Catalog # | PA5-59570 |
Price | |
Order / More Info | CMPK2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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