产品详情 |
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Antigenic Specificity | POLE2/DNA Polymerase epsilon Subunit 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunoprecipitation: 2-10 µg/mg lysate |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | POLE2/DNA Polymerase epsilon Subunit 2 Polyclonal Antibody. DNA replication, recombination and repair, all of which are necessary for genome stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. Exonucleases involved in these processes include DNA polymerases, including DNA pol delta and epsilon. DNA pol delta consists of two subunits-p125 which interacts directly with the sliding DNA clamp protein PCNA, and p50. DNA pol delta can be regulated by cell cycle proteins. DNA pol epsilon is a multiple subunit enzyme, the catalytic subunit of which is encoded |
Immunogen | n/a |
Other Names | DNA polymerase epsilon subunit 2, DNA polymerase II subunit 2, DNA polymerase epsilon subunit B, POLE2, DPE2, DNA pol epsilon2, DNA pol epsilonB, DNA pol epsilon B, DNA pol epsilon2, DNApol epsilon2, DNA pol epsilonB, DNApol epsilonB |
Gene, Accession # | Entrez: 5427; Uniprot: P56282 |
Catalog # | A304-858A |
Price | |
Order / More Info | POLE2/DNA Polymerase epsilon Subunit 2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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