| 产品详情 |
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| Antigenic Specificity | CRALBP |
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| Clone | B2 |
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| Host Species | Mouse |
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| Reactive Species | bovine, human, mouse, nonhuman primate, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay Dependent, Immunofluorescence: 1 µg/mL, Immunohistochemistry (Frozen): 1 µg/mL, Immunoprecipitation: Assay dependent, Western Blot: 0.02 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CRALBP Monoclonal Antibody (B2). Cellular retinaldehyde-binding protein (CRALBP) plays an important role in the regeneration of 11-cis-retinal for use in rod visual pigments such as opsin and rhodopsin. Once 11-cis-retinal is photoisomerized in the rod outer segment, it is converted to all-trans-retinal and further modified into all-trans-retinol. All-trans-retinol then diffuses into the retinal pigment epithelium (RPE) to be converted back to 11-cis-retinol and further oxidized into 11-cis-retinal (both by CRALBP). Genetic mutations involving CRALBP's lack of function have been linked to visual disease such as bothnia dystrophy, retinitis punctata albescens, retina pigmentosa, and Newfoundland rod-cone dystrophy. The presence of CRALBP ser |
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| Immunogen | n/a |
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| Other Names | Cellular Retinaldehyde-Binding Protein |
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| Gene, Accession # | Entrez: 19771, 282038, 293049, 6017; Uniprot: P10123, P12271, Q9Z275 |
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| Catalog # | MA1-813 |
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| Price | |
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| Order / More Info | CRALBP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11839540, 17460296, 20398651, 20678804, 20957344, 21642627, 21743014, 22615985, 22940108, 23769334, 24255038, 26121260, 26199951, 26396267, 26876013, 27009841, 27112176, 28191760, 28202390 |
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