| 产品详情 |
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| Antigenic Specificity | Rb |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rb Polyclonal Antibody. Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia. Phosphorylation of Rb at S608 depends on CDK4. |
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| Immunogen | n/a |
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| Other Names | Retinoblastoma |
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| Gene, Accession # | Entrez: 5925; Uniprot: P06400 |
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| Catalog # | PA1-38555 |
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| Price | |
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| Order / More Info | Rb Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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