| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Rb |
|---|
| Clone | 1F8 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 500 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): Assay dependent, Immunoprecipitation: Assay dependent, Western Blot: 1:100 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Rb Monoclonal Antibody (1F8). The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
|---|
| Immunogen | n/a |
|---|
| Other Names | OSRC, RB, p105-Rb, pRb, pp110 |
|---|
| Gene, Accession # | Entrez: 19645, 24708, 5925; Uniprot: P06400, P13405, P33568 |
|---|
| Catalog # | MA1-34070 |
|---|
| Price | |
|---|
| Order / More Info | Rb Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 11306450, 11489836, 11514621, 12496279, 14999779, 15082007, 15885897, 16624482, 17046054, 17212786, 17289874, 17470365, 17635520, 19009304, 19107770, 19276448, 19585502, 20215420, 20404506, 20680693, 21190189, 21410763, 21412768, 21878508, 23254264, 24735260, 24788530, 25501126, 27899422 |
|---|
| 产品资料 |
|
|