| 产品详情 |
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| Antigenic Specificity | Rb |
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| Clone | 1F8 (Rb1) |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:10-1:200, Immunofluorescence: 1:10-1:200, Immunohistochemistry (Paraffin): 1-2 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rb Monoclonal Antibody (1F8 (Rb1)). Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia. |
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| Immunogen | n/a |
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| Other Names | retinoblastoma suspectibility protein, retinoblastoma-associated protein |
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| Gene, Accession # | Entrez: 19645, 5925; Uniprot: P06400, P13405 |
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| Catalog # | MA5-11387 |
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| Price | |
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| Order / More Info | Rb Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11306450, 11489836, 14999779, 15082007, 15220371, 15557214, 15885897, 16624482, 17046054, 17212786, 17470365, 17635520, 17913384, 20680693, 21190189, 21412768, 23254264 |
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