产品详情 |
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Antigenic Specificity | CALCOCO1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, canine, equine, guinea pig, human, mouse, rabbit, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 0.2-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CALCOCO1 Polyclonal Antibody. Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions. Seems to enhance ino |
Immunogen | n/a |
Other Names | Calcium binding and Coiled-coil domain 1, Cocoa, KIAA1536, PP13275, calphoglin |
Gene, Accession # | Entrez: 100064155, 100337884, 100729752, 246047, 486505, 538675, 57658, 67488; Uniprot: Q2KJ21, Q66HR5, Q8CGU1, Q9P1Z2 |
Catalog # | PA5-44788 |
Price | |
Order / More Info | CALCOCO1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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