产品详情 |
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Antigenic Specificity | CD18 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | mouse |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 100 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 10 µL/1x10^6 cells |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD18 Polyclonal Antibody, FITC. CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes. CD18 can combine with integrin molecules CD11a-c to form heterodimers at the cell surface, and these heterodimers are known to participate in the process of cell adhesion as well as cell-surface mediated signaling. CD18 forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18). In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits, and these integrins are essential for proper leukocyte migration, |
Immunogen | n/a |
Other Names | Cd18, LAD, LCAMB, Lfa1, MF17, Integrin beta-2 subunit, ITGB2, cluster designation 18 |
Gene, Accession # | Entrez: 16414; Uniprot: P11835 |
Catalog # | PA5-46882 |
Price | |
Order / More Info | CD18 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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