| 产品详情 |
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| Antigenic Specificity | CD18 |
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| Clone | WT.3 |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 500 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1 µg/test, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD18 Monoclonal Antibody (WT.3). CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes. CD18 can combine with integrin molecules CD11a-c to form heterodimers at the cell surface, and these heterodimers are known to participate in the process of cell adhesion as well as cell-surface mediated signaling. CD18 forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18). In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits, and these integrins are essential for proper leukocyte migration |
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| Immunogen | n/a |
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| Other Names | Cd18, LAD, LCAMB, Lfa1, MF17, Integrin beta-2 subunit, ITGB2, cluster designation 18 |
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| Gene, Accession # | Entrez: 309684 |
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| Catalog # | MA1817 |
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| Price | |
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| Order / More Info | CD18 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10402448, 11121797, 9759893 |
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