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Antigenic Specificity | CD18 |
Clone | TS1/18 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 200 ug |
Concentration | n/a |
Applications | Flow Cytometry: 0.5 µg/test, Immunocytochemistry: 1:10-1:100, Immunofluorescence: 1:10-1:100, Inhibition Assays: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD18 Monoclonal Antibody (TS1/18). CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes. CD18 can combine with integrin molecules CD11a-c to form heterodimers at the cell surface, and these heterodimers are known to participate in the process of cell adhesion as well as cell-surface mediated signaling. CD18 forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18). In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits, and these integrins are essential for proper leukocyte migrati |
Immunogen | n/a |
Other Names | Cd18, LAD, LCAMB, Lfa1, MF17, Integrin beta-2 subunit, ITGB2, cluster designation 18 |
Gene, Accession # | Entrez: 3689; Uniprot: P05107 |
Catalog # | MA1810 |
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Order / More Info | CD18 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10352300, 10626904, 10670580, 11133767, 11245598, 11781316, 12032326, 12403782, 12796480, 12798306, 12799283, 1361864, 14747358, 15147444, 15226304, 15579466, 15814589, 15944315, 16009719, 16626518, 16897582, 17114441, 17311092, 17587330, 19454674, 19819295, 24312591, 8648124, 8978279, 9534971, 9600959, 9611129 |
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