| 产品详情 |
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| Antigenic Specificity | CD177 |
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| Clone | MEM-166 |
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| Host Species | Mouse |
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| Reactive Species | human, nonhuman primate |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD177 Monoclonal Antibody (MEM-166). CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN). |
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| Immunogen | n/a |
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| Other Names | HNA-2a, HNA2A, NB1, NB1 GP, PRV-1, PRV1, CD177 antigen, NB1 glycoprotein, cell surface receptor, human neutrophil alloantigen 2a, polycythemia rubra vera 1, polycythemia rubra vera protein 1 |
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| Gene, Accession # | Entrez: 57126; Uniprot: Q8N6Q3 |
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| Catalog # | MA1-19250 |
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| Price | |
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| Order / More Info | CD177 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26024230, 26149790 |
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