产品详情 |
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Antigenic Specificity | CD176 |
Clone | A78-G/A7 |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgM, kappa |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunohistochemistry (Paraffin): 1:25-1:50 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD176 Monoclonal Antibody (A78-G/A7). The Thomsen-Fridenreich antigen acts as an oncofetal antigen, with low expression in normal adult tissues but increasing to fetal levels of expression in hyperplasia or malignancy. It is considered as a pan-carcinoma marker. This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cel |
Immunogen | n/a |
Other Names | TFA |
Gene, Accession # | n/a |
Catalog # | MA5-13466 |
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Order / More Info | CD176 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 24001121 |
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